| Host: | Mouse |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-Transferrin for use in WB, IHC-P and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 1G7-8D7-4F9 |
| Conjugation: | Unconjugated |
| Isotype: | IgG1 |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification: | Affinity Purified |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100ELISA 1:10000 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | TF |
| Gene ID: | 7018 |
| Uniprot ID: | TRFE_HUMAN |
| Immunogen: | Purified recombinant protein expressed in E.coli. |
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Function | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. (Microbial infection) Serves as an iron source for Neisseria species, which capture the protein and extract its iron for their own use. (Microbial infection) Serves as an iron source for parasite T.brucei (strain 427), which capture TF via its own transferrin receptor ESAG6:ESAG7 and extract its iron for its own use. |
| Protein Name | SerotransferrinTransferrinBeta-1 Metal-Binding GlobulinSiderophilin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-381426Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-8957275Reactome: R-HSA-917937Reactome: R-HSA-917977 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Serotransferrin antibodyAnti-Transferrin antibodyAnti-Beta-1 Metal-Binding Globulin antibodyAnti-Siderophilin antibodyAnti-TF antibodyAnti-PRO1400 antibody |
Information sourced from Uniprot.org
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