| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-TRAF3IP2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:2000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
TRAF3IP2 |
| Gene ID: |
10758 |
| Uniprot ID: |
CIKS_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_679211.1; NP_001157753.1 |
| Specificity: |
This antibody is expected to recognise reported isoforms 2 and 3 (NP_679211.1; NP_001157753.1). |
| Immunogen Sequence: |
PDTGHDSDKSDQ |
| Function | E3 ubiquitin ligase that catalyzes 'Lys-63'-linked polyubiquitination of target protein, enhancing protein-protein interaction and cell signaling. Transfers ubiquitin from E2 ubiquitin-conjugating enzyme UBE2V1-UBE2N to substrate protein. Essential adapter molecule in IL17A-mediated signaling. Upon IL17A stimulation, interacts with IL17RA and IL17RC receptor chains through SEFIR domains and catalyzes 'Lys-63'-linked polyubiquitination of TRAF6, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways. |
| Protein Name | E3 Ubiquitin Ligase Traf3ip2Adapter Protein CiksConnection To Ikk And Sapk/JnkE3 Ubiquitin-Protein Ligase CiksNuclear Factor Nf-Kappa-B Activator 1Act1Traf3-Interacting Protein 2 |
| Alternative Antibody Names | Anti-E3 Ubiquitin Ligase Traf3ip2 antibodyAnti-Adapter Protein Ciks antibodyAnti-Connection To Ikk And Sapk/Jnk antibodyAnti-E3 Ubiquitin-Protein Ligase Ciks antibodyAnti-Nuclear Factor Nf-Kappa-B Activator 1 antibodyAnti-Act1 antibodyAnti-Traf3-Interacting Protein 2 antibodyAnti-TRAF3IP2 antibodyAnti-C6orf2 antibodyAnti-C6orf4 antibodyAnti-C6orf5 antibodyAnti-C6orf6 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
