Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TRAF3-interacting protein 1 (221-270 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TRAF3IP1 |
Gene ID: |
26146 |
Uniprot ID: |
MIPT3_HUMAN |
Immunogen Region: |
221-270 aa |
Specificity: |
MIP-T3 Polyclonal Antibody detects endogenous levels of MIP-T3 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human MIPT3 at the amino acid range 221-270 |
Function | Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis. |
Protein Name | Traf3-Interacting Protein 1Interleukin-13 Receptor Alpha 1-Binding Protein 1Intraflagellar Transport Protein 54 HomologMicrotubule-Interacting Protein Associated With Traf3Mip-T3 |
Database Links | Reactome: R-HSA-5620924 |
Cellular Localisation | CytoplasmCytoskeletonCell ProjectionCiliumCilium AxonemeCilium Basal BodyMicrotubulesIn The CiliumIt Is Observed At The Ciliary BaseCiliary Transition Zone And Ciliary Tip |
Alternative Antibody Names | Anti-Traf3-Interacting Protein 1 antibodyAnti-Interleukin-13 Receptor Alpha 1-Binding Protein 1 antibodyAnti-Intraflagellar Transport Protein 54 Homolog antibodyAnti-Microtubule-Interacting Protein Associated With Traf3 antibodyAnti-Mip-T3 antibodyAnti-TRAF3IP1 antibodyAnti-IFT54 antibodyAnti-MIPT3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance