Anti-TRAF3IP1 antibody (221-270 aa) (STJ94133)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human MIPT3 at the amino acid range 221-270
General Information
| Short Description | Rabbit polyclonal anti-TRAF3-interacting protein 1 (221-270 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRAF3IP1 |
| Gene ID | 26146 |
| Uniprot ID | MIPT3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human MIPT3 at the amino acid range 221-270 |
| Immunogen Region | 221-270 aa |
| Specificity | MIP-T3 Polyclonal Antibody detects endogenous levels of MIP-T3 protein. |
Additional Info
| Function | Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels. Involved in ciliogenesis. |
| Protein Name | Traf3-Interacting Protein 1Interleukin-13 Receptor Alpha 1-Binding Protein 1Intraflagellar Transport Protein 54 HomologMicrotubule-Interacting Protein Associated With Traf3Mip-T3 |
| Database Links | Reactome: R-HSA-5620924 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionCiliumCilium AxonemeCilium Basal BodyMicrotubulesIn The CiliumIt Is Observed At The Ciliary BaseCiliary Transition Zone And Ciliary Tip |
| Alternative Antibody Names | Anti-Traf3-Interacting Protein 1 antibodyAnti-Interleukin-13 Receptor Alpha 1-Binding Protein 1 antibodyAnti-Intraflagellar Transport Protein 54 Homolog antibodyAnti-Microtubule-Interacting Protein Associated With Traf3 antibodyAnti-Mip-T3 antibodyAnti-TRAF3IP1 antibodyAnti-IFT54 antibodyAnti-MIPT3 antibody |
Information sourced from Uniprot.org