| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-TNF receptor-associated factor 1 (191-240 aa) is suitable for use in Western Blot and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000ELISA 1:10000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TRAF1 |
| Gene ID: | 7185 |
| Uniprot ID: | TRAF1_HUMAN |
| Immunogen Region: | 191-240 aa |
| Specificity: | TRAF1 Polyclonal Antibody detects endogenous levels of TRAF1 |
| Immunogen: | Synthesized peptide derived from TRAF1 at the amino acid range 191-240 |
| Function | Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiquitination of target proteins, such as MAP3K14. The TRAF1/TRAF2 complex recruits the antiapoptotic E3 protein-ubiquitin ligases BIRC2 and BIRC3 to TNFRSF1B/TNFR2. |
| Protein Name | Tnf Receptor-Associated Factor 1Epstein-Barr Virus-Induced Protein 6 |
| Database Links | Reactome: R-HSA-5357905Reactome: R-HSA-5357956 |
| Alternative Antibody Names | Anti-Tnf Receptor-Associated Factor 1 antibodyAnti-Epstein-Barr Virus-Induced Protein 6 antibodyAnti-TRAF1 antibodyAnti-EBI6 antibody |
Information sourced from Uniprot.org