• Western blot analysis of extracts of various cell lines, using TCTP/TCTP/TPT1 antibody (STJ27395) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-TPT1 antibody (1-172) (STJ27395)

SKU:
STJ27395

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TPT1 (1-172) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TPT1
Gene ID: 7178
Uniprot ID: TCTP_HUMAN
Immunogen Region: 1-172
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TCTP/TCTP/TPT1 (NP_003286.1).
Immunogen Sequence: MIIYRDLISHDEMFSDIYKI REIADGLCLEVEGKMVSRTE GNIDDSLIGGNASAEGPEGE GTESTVITGVDIVMNHHLQE TSFTKEAYKKYIKDYMKSIK GKLEEQRPERVKPFMTGAAE QIKHILANFKNYQFFIGENM NPDGMVALLDYREDGVTPYM IFFKDGLEMEKC
Tissue Specificity Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.
Function Involved in calcium binding and microtubule stabilization. Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein.
Protein Name Translationally-Controlled Tumor Protein
Tctp
Fortilin
Histamine-Releasing Factor
Hrf
P23
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Translationally-Controlled Tumor Protein antibody
Anti-Tctp antibody
Anti-Fortilin antibody
Anti-Histamine-Releasing Factor antibody
Anti-Hrf antibody
Anti-P23 antibody
Anti-TPT1 antibody

Information sourced from Uniprot.org

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