| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-TPT1 (1-172) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TPT1 |
| Gene ID: |
7178 |
| Uniprot ID: |
TCTP_HUMAN |
| Immunogen Region: |
1-172 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TCTP/TCTP/TPT1 (NP_003286.1). |
| Immunogen Sequence: |
MIIYRDLISHDEMFSDIYKI REIADGLCLEVEGKMVSRTE GNIDDSLIGGNASAEGPEGE GTESTVITGVDIVMNHHLQE TSFTKEAYKKYIKDYMKSIK GKLEEQRPERVKPFMTGAAE QIKHILANFKNYQFFIGENM NPDGMVALLDYREDGVTPYM IFFKDGLEMEKC |
| Tissue Specificity | Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate. |
| Function | Involved in calcium binding and microtubule stabilization. Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein. |
| Protein Name | Translationally-Controlled Tumor ProteinTctpFortilinHistamine-Releasing FactorHrfP23 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Translationally-Controlled Tumor Protein antibodyAnti-Tctp antibodyAnti-Fortilin antibodyAnti-Histamine-Releasing Factor antibodyAnti-Hrf antibodyAnti-P23 antibodyAnti-TPT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
