| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TPI1 |
| Gene ID: | 7167 |
| Uniprot ID: | TPIS_HUMAN |
| Immunogen Region: | 1-249 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-249 of human TPI1 (NP_000356.1). |
| Immunogen Sequence: | MAPSRKFFVGGNWKMNGRKQ SLGELIGTLNAAKVPADTEV VCAPPTAYIDFARQKLDPKI AVAAQNCYKVTNGAFTGEIS PGMIKDCGATWVVLGHSERR HVFGESDELIGQKVAHALAE GLGVIACIGEKLDEREAGIT EKVVFEQTKVIADNVKDWSK VVLAYEPVWAIGTGKTATPQ QAQEVHEKLRGWLKSNVSDA VAQSTRIIYGGSVTGATCKE LASQPDVDGFLVGGASLKP |
| Function | Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis. It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids. |
| Protein Name | Triosephosphate IsomeraseTimMethylglyoxal SynthaseTriose-Phosphate Isomerase |
| Database Links | Reactome: R-HSA-70171Reactome: R-HSA-70263 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Triosephosphate Isomerase antibodyAnti-Tim antibodyAnti-Methylglyoxal Synthase antibodyAnti-Triose-Phosphate Isomerase antibodyAnti-TPI1 antibodyAnti-TPI antibody |
Information sourced from Uniprot.org