Anti-TNK1 antibody (600-666) {FITC} (STJ506151)

SKU:
STJ506151-100

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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TNK1 (600-666) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.5-1.5 µg/µl
Dilution Range: WB: 1:500-1:5, 000
ELISA: 1:50, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: TNK1
Gene ID: 8711
Uniprot ID: TNK1_HUMAN
Immunogen Region: 600-666
Immunogen: Synthetic peptide taken within amino acid region 600-666 on human Non-receptor tyrosine-protein kinase TNK1.
Tissue Specificity Expressed in all umbilical cord blood, bone marrow and adult blood cell sub-populations and in several leukemia cell lines. Highly expressed in fetal blood, brain, lung, liver and kidney. Detected at lower levels in adult prostate, testis, ovary, small intestine and colon. Not expressed in adult lung, liver, kidney or brain.
Post Translational Modifications Autophosphorylated on tyrosine residues.
Function Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Protein Name Non-Receptor Tyrosine-Protein Kinase Tnk1
Cd38 Negative Kinase 1
Cellular Localisation Cytoplasm
Membrane
Peripheral Membrane Protein
Alternative Antibody Names Anti-Non-Receptor Tyrosine-Protein Kinase Tnk1 antibody
Anti-Cd38 Negative Kinase 1 antibody
Anti-TNK1 antibody

Information sourced from Uniprot.org

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