Post Translational Modifications | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated. |
Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 25Apo-3Apoptosis-Inducing Receptor AirApoptosis-Mediating Receptor Dr3Apoptosis-Mediating Receptor TrampDeath Receptor 3Lymphocyte-Associated Receptor Of DeathLardProtein WslProtein Wsl-1 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 9: Cell MembraneIsoform 11: Cell MembraneIsoform 3: SecretedIsoform 4: SecretedIsoform 5: SecretedIsoform 6: SecretedIsoform 7: SecretedIsoform 8: SecretedIsoform 10: SecretedIsoform 12: Secreted |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 25 antibodyAnti-Apo-3 antibodyAnti-Apoptosis-Inducing Receptor Air antibodyAnti-Apoptosis-Mediating Receptor Dr3 antibodyAnti-Apoptosis-Mediating Receptor Tramp antibodyAnti-Death Receptor 3 antibodyAnti-Lymphocyte-Associated Receptor Of Death antibodyAnti-Lard antibodyAnti-Protein Wsl antibodyAnti-Protein Wsl-1 antibodyAnti-TNFRSF25 antibodyAnti-APO3 antibodyAnti-DDR3 antibodyAnti-DR3 antibodyAnti-TNFRSF12 antibodyAnti-WSL antibodyAnti-WSL1 antibodyAnti-UNQ455 antibodyAnti-PRO779 antibody |
Information sourced from Uniprot.org