Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Tumor necrosis factor receptor superfamily member 25 (230-310 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TNFRSF25 |
Gene ID: |
8718 |
Uniprot ID: |
TNR25_HUMAN |
Immunogen Region: |
230-310 aa |
Specificity: |
DR3 Polyclonal Antibody detects endogenous levels of DR3 protein. |
Immunogen: |
Synthesized peptide derived from DR3 at the amino acid range 230-310 |
Post Translational Modifications | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated. |
Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 25Apo-3Apoptosis-Inducing Receptor AirApoptosis-Mediating Receptor Dr3Apoptosis-Mediating Receptor TrampDeath Receptor 3Lymphocyte-Associated Receptor Of DeathLardProtein WslProtein Wsl-1 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 9: Cell MembraneIsoform 11: Cell MembraneIsoform 3: SecretedIsoform 4: SecretedIsoform 5: SecretedIsoform 6: SecretedIsoform 7: SecretedIsoform 8: SecretedIsoform 10: SecretedIsoform 12: Secreted |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 25 antibodyAnti-Apo-3 antibodyAnti-Apoptosis-Inducing Receptor Air antibodyAnti-Apoptosis-Mediating Receptor Dr3 antibodyAnti-Apoptosis-Mediating Receptor Tramp antibodyAnti-Death Receptor 3 antibodyAnti-Lymphocyte-Associated Receptor Of Death antibodyAnti-Lard antibodyAnti-Protein Wsl antibodyAnti-Protein Wsl-1 antibodyAnti-TNFRSF25 antibodyAnti-APO3 antibodyAnti-DDR3 antibodyAnti-DR3 antibodyAnti-TNFRSF12 antibodyAnti-WSL antibodyAnti-WSL1 antibodyAnti-UNQ455 antibodyAnti-PRO779 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance