Anti-TNFRSF25 antibody (230-310 aa) (STJ96500)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from DR3 at the amino acid range 230-310
General Information
| Short Description | Rabbit polyclonal anti-Tumor necrosis factor receptor superfamily member 25 (230-310 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC-P 1:100-300ELISA 1:20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFRSF25 |
| Gene ID | 8718 |
| Uniprot ID | TNR25_HUMAN |
| Immunogen | Synthesized peptide derived from DR3 at the amino acid range 230-310 |
| Immunogen Region | 230-310 aa |
| Specificity | DR3 Polyclonal Antibody detects endogenous levels of DR3 protein. |
Additional Info
| Post Translational Modifications | (Microbial infection) Glycosylated at Arg-352 by enteropathogenic E.coli protein NleB1. Glycosylated. |
| Function | Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 25Apo-3Apoptosis-Inducing Receptor AirApoptosis-Mediating Receptor Dr3Apoptosis-Mediating Receptor TrampDeath Receptor 3Lymphocyte-Associated Receptor Of DeathLardProtein WslProtein Wsl-1 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 9: Cell MembraneIsoform 11: Cell MembraneIsoform 3: SecretedIsoform 4: SecretedIsoform 5: SecretedIsoform 6: SecretedIsoform 7: SecretedIsoform 8: SecretedIsoform 10: SecretedIsoform 12: Secreted |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 25 antibodyAnti-Apo-3 antibodyAnti-Apoptosis-Inducing Receptor Air antibodyAnti-Apoptosis-Mediating Receptor Dr3 antibodyAnti-Apoptosis-Mediating Receptor Tramp antibodyAnti-Death Receptor 3 antibodyAnti-Lymphocyte-Associated Receptor Of Death antibodyAnti-Lard antibodyAnti-Protein Wsl antibodyAnti-Protein Wsl-1 antibodyAnti-TNFRSF25 antibodyAnti-APO3 antibodyAnti-DDR3 antibodyAnti-DR3 antibodyAnti-TNFRSF12 antibodyAnti-WSL antibodyAnti-WSL1 antibodyAnti-UNQ455 antibodyAnti-PRO779 antibody |
Information sourced from Uniprot.org