| Short Description : | Rabbit polyclonal anti-SLIT and NTRK-like protein 1 (230-310 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | SLITRK1 |
| Gene ID: | 114798 |
| Uniprot ID: | SLIK1_HUMAN |
| Immunogen: | Synthesized peptide derived from the human protein at the amino acid range 230-310 |
| Immunogen Region: | 230-310 aa |
| Specificity: | SLIK1 Polyclonal Antibody detects endogenous levels of protein. |
| Post Translational Modifications | Undergoes proteolytic cleavage that results in shedding of the ectodomain and cleavage of the C-terminal cytoplasmic tail. Glycosylated. Phosphorylation at Ser-695 is necessary for proper function in promoting neurite outgrowth. |
| Function | It is involved in synaptogenesis and promotes excitatory synapse differentiation. Enhances neuronal dendrite outgrowth. |
| Protein Name | Slit And Ntrk-Like Protein 1Leucine-Rich Repeat-Containing Protein 12 |
| Database Links | Reactome: R-HSA-388844 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedSynapse |
| Alternative Antibody Names | Anti-Slit And Ntrk-Like Protein 1 antibodyAnti-Leucine-Rich Repeat-Containing Protein 12 antibodyAnti-SLITRK1 antibodyAnti-KIAA1910 antibodyAnti-LRRC12 antibodyAnti-UNQ233 antibodyAnti-PRO266 antibody |
Information sourced from Uniprot.org
