| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TNFRSF13B |
| Gene ID: | 23495 |
| Uniprot ID: | TR13B_HUMAN |
| Immunogen Region: | 184-293 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-156 of human TNFRSF13B (NP_036584.1). |
| Immunogen Sequence: | SGLGRSRRGGRSRVDQEERF PQGLWTGVAMRSCPEEQYWD PLLGTCMSCKTICNHQSQRT CAAFCRSLSCRKEQGKFYDH LLRDCISCASICGQHPKQCA YFCENKLRSPVNLPPELRRQ RSGEVENNSDNSGRYQGLEH RGSEASPALPGLKLS |
| Tissue Specificity | Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells. |
| Function | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 13bTransmembrane Activator And Caml InteractorCd Antigen Cd267 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 13b antibodyAnti-Transmembrane Activator And Caml Interactor antibodyAnti-Cd Antigen Cd267 antibodyAnti-TNFRSF13B antibodyAnti-TACI antibody |
Information sourced from Uniprot.org