Anti-TNFRSF13B antibody (184-293) (STJ27625)

SKU:
STJ27625

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TNFRSF13B (184-293) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TNFRSF13B
Gene ID: 23495
Uniprot ID: TR13B_HUMAN
Immunogen Region: 184-293
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 184-293 of human TNFRSF13B (NP_036584.1).
Immunogen Sequence: CFLKKRGDPCSCQPRSRPRQ SPAKSSQDHAMEAGSPVSTS PEPVETCSFCFPECRAPTQE SAVTPGTPDPTCAGRWGCHT RTTVLQPCPHIPDSGLGIVC VPAQEGGPGA
Tissue Specificity Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells.
Function Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.
Protein Name Tumor Necrosis Factor Receptor Superfamily Member 13b
Transmembrane Activator And Caml Interactor
Cd Antigen Cd267
Database Links Reactome: R-HSA-5669034
Cellular Localisation Membrane
Single-Pass Type Iii Membrane Protein
Alternative Antibody Names Anti-Tumor Necrosis Factor Receptor Superfamily Member 13b antibody
Anti-Transmembrane Activator And Caml Interactor antibody
Anti-Cd Antigen Cd267 antibody
Anti-TNFRSF13B antibody
Anti-TACI antibody

Information sourced from Uniprot.org

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