Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TNFRSF13B (184-293) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TNFRSF13B |
Gene ID: |
23495 |
Uniprot ID: |
TR13B_HUMAN |
Immunogen Region: |
184-293 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 184-293 of human TNFRSF13B (NP_036584.1). |
Immunogen Sequence: |
CFLKKRGDPCSCQPRSRPRQ SPAKSSQDHAMEAGSPVSTS PEPVETCSFCFPECRAPTQE SAVTPGTPDPTCAGRWGCHT RTTVLQPCPHIPDSGLGIVC VPAQEGGPGA |
Tissue Specificity | Highly expressed in spleen, thymus, small intestine and peripheral blood leukocytes. Expressed in resting B-cells and activated T-cells, but not in resting T-cells. |
Function | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 13bTransmembrane Activator And Caml InteractorCd Antigen Cd267 |
Database Links | Reactome: R-HSA-5669034 |
Cellular Localisation | MembraneSingle-Pass Type Iii Membrane Protein |
Alternative Antibody Names | Anti-Tumor Necrosis Factor Receptor Superfamily Member 13b antibodyAnti-Transmembrane Activator And Caml Interactor antibodyAnti-Cd Antigen Cd267 antibodyAnti-TNFRSF13B antibodyAnti-TACI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance