Tissue Specificity | Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. |
Post Translational Modifications | Hemoregulatory peptide AcSDKP: AcSDKP is inactivated by ACE, which removes the dipeptide Lys-Pro from its C-terminus. |
Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Hemoregulatory peptide AcSDKP: Potent inhibitor of bone marrow derived stem cell differentiation. Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. |
Protein Name | Thymosin Beta-4T Beta-4Fx Cleaved Into - Hemoregulatory Peptide AcsdkpAc-Ser-Asp-Lys-ProN-Acetyl-SdkpAcsdkpSeraspenide |
Database Links | Reactome: R-HSA-114608 |
Cellular Localisation | CytoplasmCytoskeleton |
Alternative Antibody Names | Anti-Thymosin Beta-4 antibodyAnti-T Beta-4 antibodyAnti-Fx Cleaved Into - Hemoregulatory Peptide Acsdkp antibodyAnti-Ac-Ser-Asp-Lys-Pro antibodyAnti-N-Acetyl-Sdkp antibodyAnti-Acsdkp antibodyAnti-Seraspenide antibodyAnti-TMSB4X antibodyAnti-TB4X antibodyAnti-THYB4 antibodyAnti-TMSB4 antibody |
Information sourced from Uniprot.org