| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMSB4X |
| Gene ID: | 7114 |
| Uniprot ID: | TYB4_HUMAN |
| Immunogen Region: | 1-44 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-44 of human TMSB4X (NP_066932.1). |
| Immunogen Sequence: | MSDKPDMAEIEKFDKSKLKK TETQEKNPLPSKETIEQEKQ AGES |
| Tissue Specificity | Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells. |
| Post Translational Modifications | Hemoregulatory peptide AcSDKP: AcSDKP is inactivated by ACE, which removes the dipeptide Lys-Pro from its C-terminus. |
| Function | Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Hemoregulatory peptide AcSDKP: Potent inhibitor of bone marrow derived stem cell differentiation. Acts by inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. |
| Protein Name | Thymosin Beta-4T Beta-4Fx Cleaved Into - Hemoregulatory Peptide AcsdkpAc-Ser-Asp-Lys-ProN-Acetyl-SdkpAcsdkpSeraspenide |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Antibody Names | Anti-Thymosin Beta-4 antibodyAnti-T Beta-4 antibodyAnti-Fx Cleaved Into - Hemoregulatory Peptide Acsdkp antibodyAnti-Ac-Ser-Asp-Lys-Pro antibodyAnti-N-Acetyl-Sdkp antibodyAnti-Acsdkp antibodyAnti-Seraspenide antibodyAnti-TMSB4X antibodyAnti-TB4X antibodyAnti-THYB4 antibodyAnti-TMSB4 antibody |
Information sourced from Uniprot.org
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