| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Transmembrane protease serine 4 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TMPRSS4 |
| Gene ID: |
56649 |
| Uniprot ID: |
TMPS4_HUMAN |
| Specificity: |
This antibody detects endogenous levels of TMPRSS4 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human TMPRSS4 |
| Post Translational Modifications | Proteolytically processed.probably by an autocatalytic mechanism. |
| Function | Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC. (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. |
| Protein Name | Transmembrane Protease Serine 4Channel-Activating Protease 2Caph2Membrane-Type Serine Protease 2Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinTransmembrane Protease Serine 4 Catalytic Chain: SecretedActivated By Cleavage And Secreted |
| Alternative Antibody Names | Anti-Transmembrane Protease Serine 4 antibodyAnti-Channel-Activating Protease 2 antibodyAnti-Caph2 antibodyAnti-Membrane-Type Serine Protease 2 antibodyAnti-Mt-Sp2 Cleaved Into - Transmembrane Protease Serine 4 Catalytic Chain antibodyAnti-TMPRSS4 antibodyAnti-TMPRSS3 antibodyAnti-UNQ776 antibodyAnti-PRO1570 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
