• Western blot analysis of extracts of various cell lines, using TMPRSS11A antibody (STJ116102) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.

Anti-TMPRSS11A antibody (300-421) (STJ116102)

SKU:
STJ116102

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TMPRSS11A (300-421) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TMPRSS11A
Gene ID: 339967
Uniprot ID: TM11A_HUMAN
Immunogen Region: 300-421
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-421 of human TMPRSS11A (NP_872412.3).
Immunogen Sequence: SASFQPNLTVHITGFGALYY GGESQNDLREARVKIISDDV CKQPQVYGNDIKPGMFCAGY MEGIYDACRGDSGGPLVTRD LKDTWYLIGIVSWGDNCGQK DKPGVYTQVTYYRNWIASKT GI
Tissue Specificity Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers.
Function Probable serine protease which may play a role in cellular senescence. Overexpression inhibits cell growth and induce G1 cell cycle arrest.
Protein Name Transmembrane Protease Serine 11a
Airway Trypsin-Like Protease 1
Epidermal Type-Ii Transmembrane Serine Protease
Esophageal Cancer-Susceptibility Gene 1 Protein
Cellular Localisation Membrane
Single-Pass Type Ii Membrane Protein
Alternative Antibody Names Anti-Transmembrane Protease Serine 11a antibody
Anti-Airway Trypsin-Like Protease 1 antibody
Anti-Epidermal Type-Ii Transmembrane Serine Protease antibody
Anti-Esophageal Cancer-Susceptibility Gene 1 Protein antibody
Anti-TMPRSS11A antibody
Anti-ECRG1 antibody
Anti-HATL1 antibody
Anti-HESP antibody

Information sourced from Uniprot.org

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