| Host: | Rabbit |
| Applications: | IF/ICC/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TMLHE |
| Gene ID: | 55217 |
| Uniprot ID: | TMLH_HUMAN |
| Immunogen Region: | 167-376 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 167-376 of human TMLHE (NP_001171726.1). |
| Immunogen Sequence: | CQSFLETNEGLKKFLQNFLL YGIAFVENVPPTQEHTEKLA ERISLIRETIYGRMWYFTSD FSRGDTAYTKLALDRHTDTT YFQEPCGIQVFHCLKHEGTG GRTLLVDGFYAAEQVLQKAP EEFELLSKVPLKHEYIEDVG ECHNHMIGIGPVLNIYPWNK ELYLIRLFKEKQNTVNRQWN SSLQCDIPERILTYRHFVSG TSIEHRGSLI |
| Tissue Specificity | All isoforms, but isoform 8, are widely expressed in adult and fetal tissues. Isoform 8 is restricted to heart and skeletal muscle. |
| Function | Converts trimethyllysine (TML) into hydroxytrimethyllysine (HTML). |
| Protein Name | Trimethyllysine Dioxygenase - MitochondrialEpsilon-Trimethyllysine 2-Oxoglutarate DioxygenaseEpsilon-Trimethyllysine HydroxylaseTml HydroxylaseTml-Alpha-Ketoglutarate DioxygenaseTml DioxygenaseTmld |
| Database Links | Reactome: R-HSA-71262 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Trimethyllysine Dioxygenase - Mitochondrial antibodyAnti-Epsilon-Trimethyllysine 2-Oxoglutarate Dioxygenase antibodyAnti-Epsilon-Trimethyllysine Hydroxylase antibodyAnti-Tml Hydroxylase antibodyAnti-Tml-Alpha-Ketoglutarate Dioxygenase antibodyAnti-Tml Dioxygenase antibodyAnti-Tmld antibodyAnti-TMLHE antibodyAnti-TMLH antibody |
Information sourced from Uniprot.org