| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TM7SF2 |
| Gene ID: |
7108 |
| Uniprot ID: |
ERG24_HUMAN |
| Immunogen Region: |
160-250 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 160-250 of human TM7SF2 (NP_003264.2). |
| Immunogen Sequence: |
LAPGGNSGNPIYDFFLGREL NPRICFFDFKYFCELRPGLI GWVLINLALLMKEAELRGSP SLAMWLVNGFQLLYVGDALW HEEAVLTTMDI |
| Tissue Specificity | Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, testis and adrenal gland, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. |
| Function | Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis. |
| Protein Name | Delta(14-Sterol Reductase Tm7sf2Delta-14-Sr3-Beta-Hydroxysterol Delta14-ReductaseAnother New Gene 1 ProteinC-14 Sterol ReductaseC14srPutative Sterol Reductase Sr-1Sterol C14-ReductaseTransmembrane 7 Superfamily Member 2 |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Microsome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Delta(14-Sterol Reductase Tm7sf2 antibodyAnti-Delta-14-Sr antibodyAnti-3-Beta-Hydroxysterol Delta antibodyAnti-14-Reductase antibodyAnti-Another New Gene 1 Protein antibodyAnti-C-14 Sterol Reductase antibodyAnti-C14sr antibodyAnti-Putative Sterol Reductase Sr-1 antibodyAnti-Sterol C14-Reductase antibodyAnti-Transmembrane 7 Superfamily Member 2 antibodyAnti-TM7SF2 antibodyAnti-ANG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and TXLNA knockout (KO) HeLa cells, using [KO Validated] TXLNA Rabbit polyclonal antibody (STJ11100765) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89702/358186/STJ11100765_1__45157.1713122500.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXLNA knockout (KO) HeLa cells, using [KO Validated] TXLNA Rabbit polyclonal antibody (STJ11100765) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")