| Host: | Rat |
| Applications: | IHC-F/FC/IF/IP |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rat monoclonal antibody anti-TLR4/MD2 is suitable for use in Immunohistochemistry, Flow Cytometry, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality : | Monoclonal |
| Clone ID : | MTS510 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration: | 100 ug/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Gene Symbol: | LY96 |
| Gene ID: | 23643 |
| Uniprot ID: | LY96_HUMAN |
| Post Translational Modifications | N-glycosylated.high-mannose. |
| Function | Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS. |
| Protein Name | Lymphocyte Antigen 96 Ly-96 Esop-1 Protein Md-2 |
| Database Links | Reactome: R-HSA-1236974 Reactome: R-HSA-140534 Reactome: R-HSA-166016 Reactome: R-HSA-166058 Reactome: R-HSA-166166 Reactome: R-HSA-2562578 Reactome: R-HSA-5602498 Reactome: R-HSA-5603041 Reactome: R-HSA-5686938 Reactome: R-HSA-936964 Reactome: R-HSA-937041 Reactome: R-HSA-937072 Reactome: R-HSA-9707616 Reactome: R-HSA-975163 Reactome: R-HSA-9820960 Reactome: R-HSA-9824878 Reactome: R-HSA-9833110 |
| Cellular Localisation | Secreted Extracellular Space Retained In The Extracellular Space At The Cell Surface By Interaction With Tlr4 |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 96 antibody Anti-Ly-96 antibody Anti-Esop-1 antibody Anti-Protein Md-2 antibody Anti-LY96 antibody Anti-ESOP1 antibody Anti-MD2 antibody |
Information sourced from Uniprot.org