| Host: | Rat |
| Applications: | IHC-F/FC/IF/IP |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rat monoclonal antibody anti-TLR4/MD2 is suitable for use in Immunohistochemistry, Flow Cytometry, Immunofluorescence and Immunoprecipitation research applications. |
| Clonality: | Monoclonal |
| Clone ID: | MTS510 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2a |
| Formulation: | PBS with 0.1% BSA and 0.02% sodium azide |
| Concentration: | 100 ug/mL |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Gene Symbol: | LY96 |
| Gene ID: | 23643 |
| Uniprot ID: | LY96_HUMAN |
| Post Translational Modifications | N-glycosylated.high-mannose. |
| Function | Binds bacterial lipopolysaccharide (LPS). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria. Enhances TLR4-dependent activation of NF-kappa-B. Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS. |
| Protein Name | Lymphocyte Antigen 96Ly-96Esop-1Protein Md-2 |
| Database Links | Reactome: R-HSA-1236974Reactome: R-HSA-140534Reactome: R-HSA-166016Reactome: R-HSA-166058Reactome: R-HSA-166166Reactome: R-HSA-2562578Reactome: R-HSA-5602498Reactome: R-HSA-5603041Reactome: R-HSA-5686938Reactome: R-HSA-936964Reactome: R-HSA-937041Reactome: R-HSA-937072Reactome: R-HSA-9707616Reactome: R-HSA-975163 |
| Cellular Localisation | SecretedExtracellular SpaceRetained In The Extracellular Space At The Cell Surface By Interaction With Tlr4 |
| Alternative Antibody Names | Anti-Lymphocyte Antigen 96 antibodyAnti-Ly-96 antibodyAnti-Esop-1 antibodyAnti-Protein Md-2 antibodyAnti-LY96 antibodyAnti-ESOP1 antibodyAnti-MD2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
