Host: |
Rabbit |
Applications: |
ELISA/ICC/IF/IHC/IP/WB |
Reactivity: |
Chimpanzee/Human/Monkey/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TLR10 (380-430) is suitable for use in ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Purification: |
Affinity Purified |
Concentration: |
0.55-0.67 µg/µl |
Dilution Range: |
WB: 1:500ELISA: 1:20, 000IP: 1:200IHC: 1:100ICC: 1:100IF: 1:100 |
Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: |
TLR10 |
Gene ID: |
81793 |
Uniprot ID: |
TLR10_HUMAN |
Immunogen Region: |
380-430 |
Immunogen: |
Synthetic peptide taken within amino acid region 380-430 on human TLR10 protein. |
Tissue Specificity | Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines. |
Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
Protein Name | Toll-Like Receptor 10Cd Antigen Cd290 |
Database Links | Reactome: R-HSA-168142Reactome: R-HSA-5603037Reactome: R-HSA-975871 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Toll-Like Receptor 10 antibodyAnti-Cd Antigen Cd290 antibodyAnti-TLR10 antibodyAnti-UNQ315 antibodyAnti-PRO358 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance