Anti-TK1 nanobody [SAA1373] (STJN000094)

Anti-TK1 nanobody [SAA1373] (STJN000094)

SKU:
STJN000094
$510.98 - $2,203.88
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Covered by St John's Laboratory Guarantee

Host: Alpaca
Applications: DB/ELISA/FC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Alpaca monoclonal nanobody anti-Thymidine Kinase-Cytosolic is suitable for use in Dot Blot, ELISA, Flow Cytometry and Western Blot research applications.
Clonality : Monoclonal
Clone ID : SAA1373
Conjugation: Unconjugated
Isotype: VHH-8His-Cys-tag
Formulation: 0.01M PBS, pH 7.4.
Purification: Purified by Nickel column.
Concentration: 1 mg/mL
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.
Gene Symbol: TK1
Gene ID: 7083
Uniprot ID: KITH_HUMAN
Function Cell-cycle-regulated enzyme of importance in nucleotide metabolism. Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate. Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c-azido-3c-deoxythymidine (AZT).
Protein Name Thymidine Kinase - Cytosolic
Database Links Reactome: R-HSA-69205
Reactome: R-HSA-73614
Cellular Localisation Cytoplasm
Alternative Nanobody Names Anti-Thymidine Kinase - Cytosolic nanobody
Anti-TK1 nanobody

Information sourced from Uniprot.org

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