• Western blot analysis of extracts of various cell lines, using TIMP2 antibody (STJ11103441) at1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
  • Western blot analysis of extracts of various cell lines, using TIMP2 antibody (STJ11103441) at1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 20s.

Anti-TIMP2 antibody (120-220 aa) [S1MR] (STJ11103441)

SKU:
STJ11103441

$174.83 - $775.58
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Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Mouse/Rat/African green monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality: Monoclonal
Clone ID: S1MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3.
Purification: Affinity purification
Concentration: Lot specific
Dilution Range: WB:1:500-1:1000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TIMP2
Gene ID: 7077
Uniprot ID: TIMP2_HUMAN
Immunogen Region: 120-220 aa
Specificity: Recombinant fusion protein containing a sequence corresponding to amino acids 120-220 of human TIMP2. (NP_003246.1).
Immunogen Sequence: GKMHITLCDFIVPWDTLSTT QKKSLNHRYQMGCECKITRC PMIPCYISSPDECLWMDWVT EKNINGHQAKFFACIKRSDG SCAWYRGAAPPKQEFLDIED P
Post Translational Modifications The activity of TIMP2 is dependent on the presence of disulfide bonds.
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Protein Name Metalloproteinase Inhibitor 2
Csc-21k
Tissue Inhibitor Of Metalloproteinases 2
Timp-2
Database Links Reactome: R-HSA-1592389
Reactome: R-HSA-6798695
Reactome: R-HSA-9839383
Cellular Localisation Secreted
Alternative Antibody Names Anti-Metalloproteinase Inhibitor 2 antibody
Anti-Csc-21k antibody
Anti-Tissue Inhibitor Of Metalloproteinases 2 antibody
Anti-Timp-2 antibody
Anti-TIMP2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance