Post Translational Modifications | The activity of TIMP2 is dependent on the presence of disulfide bonds. |
Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. |
Protein Name | Metalloproteinase Inhibitor 2Csc-21kTissue Inhibitor Of Metalloproteinases 2Timp-2 |
Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-6798695Reactome: R-HSA-9839383 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Metalloproteinase Inhibitor 2 antibodyAnti-Csc-21k antibodyAnti-Tissue Inhibitor Of Metalloproteinases 2 antibodyAnti-Timp-2 antibodyAnti-TIMP2 antibody |
Information sourced from Uniprot.org