Anti-TIMP-2 antibody [3A4] (STJ16100715)

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STJ16100715-1
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Short Description :Mouse monoclonal anti-TIMP-2 for use in IHC-P, IHC-F and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC-P/IHC-F/WB
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :3A4
Isotype:IgG1
Conjugation:Unconjugated
Formulation:Culture supernatant with 0.05% sodium azide
Storage Instruction:Store at 2-8°C for up to 1-year, upon receipt.
Gene Symbol:TIMP2
Gene ID:7077
Uniprot ID:TIMP2_HUMAN
Immunogen:human TIMP-2 peptide: DSGNDIYGNPI
Post Translational Modifications The activity of TIMP2 is dependent on the presence of disulfide bonds.
Function Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.
Protein Name Metalloproteinase Inhibitor 2
Csc-21k
Tissue Inhibitor Of Metalloproteinases 2
Timp-2
Database Links Reactome: R-HSA-1592389
Reactome: R-HSA-6798695
Reactome: R-HSA-9839383
Cellular Localisation Secreted
Alternative Antibody Names Anti-Metalloproteinase Inhibitor 2 antibody
Anti-Csc-21k antibody
Anti-Tissue Inhibitor Of Metalloproteinases 2 antibody
Anti-Timp-2 antibody
Anti-TIMP2 antibody

Information sourced from Uniprot.org

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