| Host: |
Mouse |
| Applications: |
IHC-P/IHC-F/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Mouse monoclonal antibody anti-TIMP-2 is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
3A4 |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG1 |
| Formulation: |
Culture supernatant with 0.05% sodium azide |
| Storage Instruction: |
Store at 2-8°C upon receipt. |
| Gene Symbol: |
TIMP2 |
| Gene ID: |
7077 |
| Uniprot ID: |
TIMP2_HUMAN |
| Immunogen: |
human TIMP-2 peptide: DSGNDIYGNPI |
| Post Translational Modifications | The activity of TIMP2 is dependent on the presence of disulfide bonds. |
| Function | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. |
| Protein Name | Metalloproteinase Inhibitor 2Csc-21kTissue Inhibitor Of Metalloproteinases 2Timp-2 |
| Database Links | Reactome: R-HSA-1592389Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Metalloproteinase Inhibitor 2 antibodyAnti-Csc-21k antibodyAnti-Tissue Inhibitor Of Metalloproteinases 2 antibodyAnti-Timp-2 antibodyAnti-TIMP2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
