Anti-TIMM17B antibody (1-172) (STJ110775)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TIMM17B (1-172) antibody for use in WB and ELISA in mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TIMM17B |
| Gene ID | 10245 |
| Uniprot ID | TI17B_HUMAN |
| Immunogen Region | 1-172 |
| Immunogen Sequence | MEEYAREPCPWRIVDDCGGA FTMGVIGGGVFQAIKGFRNA PVGIRHRLRGSANAVRIRAP QIGGSFAVWGGLFSTIDCGL VRLRGKEDPWNSITSGALTG AVLAARSGPLAMVGSAMMGG ILLALIEGVGILLTRYTAQQ FRNAPPFLEDPSQLPPKDGT PAPGYPSYQQYH |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TIMM17B (NP_005825.1). |
Additional Info
| Tissue Specificity | Expression is abundant in heart and skeletal muscle, intermediate in brain, and weak in pancreas, placenta, kidney and liver. |
| Post Translational Modifications | Forms one disulfide bond. |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim17-B |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim17-B antibodyAnti-TIMM17B antibodyAnti-TIM17B antibodyAnti-JM3 antibody |
Information sourced from Uniprot.org