| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TIMM17B |
| Gene ID: | 10245 |
| Uniprot ID: | TI17B_HUMAN |
| Immunogen Region: | 1-172 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TIMM17B (NP_005825.1). |
| Immunogen Sequence: | MEEYAREPCPWRIVDDCGGA FTMGVIGGGVFQAIKGFRNA PVGIRHRLRGSANAVRIRAP QIGGSFAVWGGLFSTIDCGL VRLRGKEDPWNSITSGALTG AVLAARSGPLAMVGSAMMGG ILLALIEGVGILLTRYTAQQ FRNAPPFLEDPSQLPPKDGT PAPGYPSYQQYH |
| Tissue Specificity | Expression is abundant in heart and skeletal muscle, intermediate in brain, and weak in pancreas, placenta, kidney and liver. |
| Post Translational Modifications | Forms one disulfide bond. |
| Function | Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. |
| Protein Name | Mitochondrial Import Inner Membrane Translocase Subunit Tim17-B |
| Database Links | Reactome: R-HSA-1268020 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim17-B antibodyAnti-TIMM17B antibodyAnti-TIM17B antibodyAnti-JM3 antibody |
Information sourced from Uniprot.org