• Western blot analysis of extracts of mouse heart, using TIMM17B antibody (STJ110775) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
  • Western blot analysis of extracts of mouse heart, using TIMM17B antibody (STJ110775) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-TIMM17B antibody (1-172) (STJ110775)

SKU:
STJ110775

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TIMM17B (1-172) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TIMM17B
Gene ID: 10245
Uniprot ID: TI17B_HUMAN
Immunogen Region: 1-172
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TIMM17B (NP_005825.1).
Immunogen Sequence: MEEYAREPCPWRIVDDCGGA FTMGVIGGGVFQAIKGFRNA PVGIRHRLRGSANAVRIRAP QIGGSFAVWGGLFSTIDCGL VRLRGKEDPWNSITSGALTG AVLAARSGPLAMVGSAMMGG ILLALIEGVGILLTRYTAQQ FRNAPPFLEDPSQLPPKDGT PAPGYPSYQQYH
Tissue Specificity Expression is abundant in heart and skeletal muscle, intermediate in brain, and weak in pancreas, placenta, kidney and liver.
Post Translational Modifications Forms one disulfide bond.
Function Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
Protein Name Mitochondrial Import Inner Membrane Translocase Subunit Tim17-B
Database Links Reactome: R-HSA-1268020
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Mitochondrial Import Inner Membrane Translocase Subunit Tim17-B antibody
Anti-TIMM17B antibody
Anti-TIM17B antibody
Anti-JM3 antibody

Information sourced from Uniprot.org

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