| Host: |
Rabbit |
| Applications: |
IHC/IF/ELISA |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Krueppel-like factor 10 and Krueppel-like factor 11 (391-440 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
KLF10KLF11 |
| Gene ID: |
70718462 |
| Uniprot ID: |
KLF10_HUMANKLF11_HUMAN |
| Immunogen Region: |
391-440 aa |
| Specificity: |
TIEG-1/2 Polyclonal Antibody detects endogenous levels of TIEG-1/2 protein. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from the human KLF10/11 at the amino acid range 391-440 |
| Function | Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock.binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis. May play a role in the cell cycle regulation. |
| Protein Name | Krueppel-Like Factor 10Egr-AlphaTransforming Growth Factor-Beta-Inducible Early Growth Response Protein 1Tgfb-Inducible Early Growth Response Protein 1Tieg-1 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Krueppel-Like Factor 10 antibodyAnti-Egr-Alpha antibodyAnti-Transforming Growth Factor-Beta-Inducible Early Growth Response Protein 1 antibodyAnti-Tgfb-Inducible Early Growth Response Protein 1 antibodyAnti-Tieg-1 antibodyAnti-KLF10 antibodyAnti-TIEG antibodyAnti-TIEG1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
