![Anti-Thyroid Peroxidase antibody [AC25] (STJ16101796)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/152302/347149/STJ16101796_1__82619.1681999422.jpg?c=1 "Anti-Thyroid Peroxidase antibody [AC25] (STJ16101796)")
![Anti-Thyroid Peroxidase antibody [AC25] (STJ16101796)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/152302/347149/STJ16101796_1__82619.1681999422.jpg?c=1 "Anti-Thyroid Peroxidase antibody [AC25] (STJ16101796)")
Anti-Thyroid Peroxidase antibody [AC25] (STJ16101796)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenProkaryotic recombinant protein containing 105 amino acids corresponding to a portion of the N-terminus of the human thyroid peroxidase molecule.
General Information
| Short Description | Mouse monoclonal anti-Thyroid Peroxidase for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AC25 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | >=10.8 mg/L |
| Dilution Range | IHC-P 1:80 |
| Formulation | Tissue culture supernatant with sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Gene Symbol | TPO |
| Gene ID | 7173 |
| Uniprot ID | PERT_HUMAN |
| Immunogen | Prokaryotic recombinant protein containing 105 amino acids corresponding to a portion of the N-terminus of the human thyroid peroxidase molecule. |
Additional Info
| Post Translational Modifications | Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part. |
| Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). |
| Protein Name | Thyroid PeroxidaseTpo |
| Database Links | Reactome: R-HSA-209968 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell Surface |
| Alternative Antibody Names | Anti-Thyroid Peroxidase antibodyAnti-Tpo antibodyAnti-TPO antibody |
Information sourced from Uniprot.org