Host: | Mouse |
Applications: | IHC-P |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Mouse monoclonal antibody anti-Thyroid Peroxidase is suitable for use in Immunohistochemistry research applications. |
Clonality : | Monoclonal |
Clone ID : | AC25 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | Tissue culture supernatant with sodium azide |
Concentration: | >=10.8 mg/L |
Dilution Range: | IHC-P 1:80 |
Storage Instruction: | Store at 2-8°C upon receipt. |
Gene Symbol: | TPO |
Gene ID: | 7173 |
Uniprot ID: | PERT_HUMAN |
Immunogen: | Prokaryotic recombinant protein containing 105 amino acids corresponding to a portion of the N-terminus of the human thyroid peroxidase molecule. |
Post Translational Modifications | Glycosylated. Heme is covalently bound through a H(2)O(2)-dependent autocatalytic process. Heme insertion is important for the delivery of protein at the cell surface. Cleaved in its N-terminal part. |
Function | Iodination and coupling of the hormonogenic tyrosines in thyroglobulin to yield the thyroid hormones T(3) and T(4). |
Protein Name | Thyroid PeroxidaseTpo |
Database Links | Reactome: R-HSA-209968 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell Surface |
Alternative Antibody Names | Anti-Thyroid Peroxidase antibodyAnti-Tpo antibodyAnti-TPO antibody |
Information sourced from Uniprot.org