| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | THRSP |
| Gene ID: | 7069 |
| Uniprot ID: | THRSP_HUMAN |
| Immunogen Region: | 1-146 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-146 of human THRSP (NP_003242.1). |
| Immunogen Sequence: | MQVLTKRYPKNCLLTVMDRY AAEVHNMEQVVMIPSLLRDV QLSGPGGQAQAEAPDLYTYF TMLKAICVDVDHGLLPREEW QAKVAGSEENGTAETEEVED ESASGELDLEAQFHLHFSSL HHILMHLTEKAQEVTRKYQE MTGQVW |
| Tissue Specificity | Mainly expressed in tissues that synthesize triglycerides. |
| Function | Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB. |
| Protein Name | Thyroid Hormone-Inducible Hepatic ProteinSpot 14 ProteinS14Spot14 |
| Database Links | Reactome: R-HSA-200425 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Thyroid Hormone-Inducible Hepatic Protein antibodyAnti-Spot 14 Protein antibodyAnti-S14 antibodyAnti-Spot14 antibodyAnti-THRSP antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100722) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89660/358158/STJ11100722_1__83995.1713122459.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100722) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
![Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100721) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89659/358157/STJ11100721_1__02526.1713122458.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CDA knockout (KO) HeLa cells, using [KO Validated] CDA Rabbit polyclonal antibody (STJ11100721) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
