| Host: |
Rabbit |
| Applications: |
WB/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: |
Affinity purification |
| Concentration: |
Lot specific |
| Dilution Range: |
WB:1:200-1:3000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
TFIP11 |
| Gene ID: |
24144 |
| Uniprot ID: |
TFP11_HUMAN |
| Immunogen Region: |
1-140 |
| Specificity: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human TFIP11 (NP_036275.1). |
| Immunogen Sequence: |
MSLSHLYRDGEGRIDDDDDE RENFEITDWDLQNEFNPNRQ RHWQTKEEATYGVWAERDSD DERPSFGGKRARDYSAPVNF ISAGLKKGAAEEAELEDSDD EEKPVKQDDFPKDFGPRKLK TGGNFKPSQKGFAGGTKSFM |
| Function | Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix. |
| Protein Name | Tuftelin-Interacting Protein 11Septin And Tuftelin-Interacting Protein 1Stip-1 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | CytoplasmNucleusIn The Nucleus Localizes To Unique Speckle Domains In Close Proximity To Nuclear Speckles And Not Identical To Paraspeckles |
| Alternative Antibody Names | Anti-Tuftelin-Interacting Protein 11 antibodyAnti-Septin And Tuftelin-Interacting Protein 1 antibodyAnti-Stip-1 antibodyAnti-TFIP11 antibodyAnti-STIP antibodyAnti-HSPC006 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
