| Function | Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form. |
| Protein Name | Transcription Factor EcTfe-CClass E Basic Helix-Loop-Helix Protein 34Bhlhe34Transcription Factor Ec-LikeHtfec-L |
| Database Links | Reactome: R-HSA-9856649 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Ec antibodyAnti-Tfe-C antibodyAnti-Class E Basic Helix-Loop-Helix Protein 34 antibodyAnti-Bhlhe34 antibodyAnti-Transcription Factor Ec-Like antibodyAnti-Htfec-L antibodyAnti-TFEC antibodyAnti-BHLHE34 antibodyAnti-TCFEC antibodyAnti-TFECL antibody |
Information sourced from Uniprot.org
