Anti-TFEC antibody (STJA0009588)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human TFEC
General Information
| Short Description | Rabbit polyclonal anti-Transcription factor EC for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TFEC |
| Gene ID | 22797 |
| Uniprot ID | TFEC_HUMAN |
| Immunogen | Synthesized peptide derived from human TFEC |
| Specificity | This antibody detects endogenous levels of TFEC at Human, Mouse, Rat |
Additional Info
| Function | Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter. Collaborates with MITF in target gene activation. Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer. Binds DNA in a homo- or heterodimeric form. |
| Protein Name | Transcription Factor EcTfe-CClass E Basic Helix-Loop-Helix Protein 34Bhlhe34Transcription Factor Ec-LikeHtfec-L |
| Database Links | Reactome: R-HSA-9856649 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Ec antibodyAnti-Tfe-C antibodyAnti-Class E Basic Helix-Loop-Helix Protein 34 antibodyAnti-Bhlhe34 antibodyAnti-Transcription Factor Ec-Like antibodyAnti-Htfec-L antibodyAnti-TFEC antibodyAnti-BHLHE34 antibodyAnti-TCFEC antibodyAnti-TFECL antibody |
Information sourced from Uniprot.org