| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TEKT4 |
| Gene ID: | 150483 |
| Uniprot ID: | TEKT4_HUMAN |
| Immunogen Region: | 1-270 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TEKT4 (NP_653306.1). |
| Immunogen Sequence: | MAQTVPPCELPCKEYDVARN TGAYTSSGLATASFRTSKYL LEEWFQNCYARYHQAFADRD QSERQRHESQQLATETQALA QRTQQDSTRTVGERLQDTHS WKSELQREMEALAAETNLLL AQKQRLERALDATEVPFSIT TDNLQCRERREHPNLVRDHV ETELLKEAELIRNIQELLKR TIMQAVSQIRLNREHKETCE MDWSDKMEAYNIDETCGRHH SQSTEVQAHPYSTTFQESA |
| Tissue Specificity | Strongly expressed in spermatozoa. Also detected at low levels in pancreas. Expressed in airway epithelial cells. |
| Post Translational Modifications | Ubiquitinated, leading to its degradation. Deubiquitinated by USP16, promoting its stability. |
| Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Contributes to normal sperm motility. |
| Protein Name | Tektin-4 |
| Cellular Localisation | CytoplasmCytoskeletonCilium AxonemeFlagellum AxonemeFound In The Abaxial (Convex) Surface Of Outer Dense Fibers In Sperm Flagella |
| Alternative Antibody Names | Anti-Tektin-4 antibodyAnti-TEKT4 antibody |
Information sourced from Uniprot.org