| Post Translational Modifications | Probably cleaved by enteroviral 2A proteinase. |
| Function | Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. |
| Protein Name | Tudor Domain-Containing Protein 3 |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicAssociated With Actively Translating PolyribosomesComponent Of Stress Granules |
| Alternative Antibody Names | Anti-Tudor Domain-Containing Protein 3 antibodyAnti-TDRD3 antibody |
Information sourced from Uniprot.org
