Anti-TDRD3 IP antibody [SAA0234] (STJA0018749)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Mouse monoclonal Tudor Domain-Containing Protein 3 antibody for use in ELISA, IF and IP in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IF/IP |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0234 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | TDRD3 |
| Gene ID | 81550 |
| Uniprot ID | TDRD3_HUMAN |
Additional Info
| Post Translational Modifications | Probably cleaved by enteroviral 2A proteinase. |
| Function | Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. Plays a role in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, acts as an antiviral factor that participates in the assembly of stress granules together with G3BP1. |
| Protein Name | Tudor Domain-Containing Protein 3 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicAssociated With Actively Translating PolyribosomesComponent Of Stress Granules |
| Alternative Antibody Names | Anti-Tudor Domain-Containing Protein 3 antibodyAnti-TDRD3 antibody |
Information sourced from Uniprot.org