| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TDO2 |
| Gene ID: | 6999 |
| Uniprot ID: | T23O_HUMAN |
| Immunogen Region: | 167-184 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TDO2 (NP_005642.1). |
| Immunogen Sequence: | GHVRDERNMLKVVSRMHRVS VILKLLVQQFSILETMTALD FNDFREYLSPASGFQSLQFR LLENKIGVLQNMRVPYNRRH YRDNFKGEENELLLKSEQEK TLLELVEAWLERTPGLEPHG FNFWGKLEKNITRGLEEEFI RIQAKEESEEKEEQVAEFQK QKEVLLSLFDEKRHEHLLSK GERRLSYRALQGALMIYFYR |
| Function | Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. |
| Protein Name | Tryptophan 2 -3-DioxygenaseTdoTryptamin 2 -3-DioxygenaseTryptophan OxygenaseToTrpoTryptophan PyrrolaseTryptophanase |
| Database Links | Reactome: R-HSA-71240 |
| Alternative Antibody Names | Anti-Tryptophan 2 -3-Dioxygenase antibodyAnti-Tdo antibodyAnti-Tryptamin 2 -3-Dioxygenase antibodyAnti-Tryptophan Oxygenase antibodyAnti-To antibodyAnti-Trpo antibodyAnti-Tryptophan Pyrrolase antibodyAnti-Tryptophanase antibodyAnti-TDO2 antibodyAnti-TDO antibody |
Information sourced from Uniprot.org