| Host: | Rabbit |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCTN2 |
| Gene ID: | 79867 |
| Uniprot ID: | TECT2_HUMAN |
| Immunogen Region: | 420-670 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 420-670 of human TCTN2 (NP_079085.2). |
| Immunogen Sequence: | VKFLSYNSGNEEELSGNPGY QLGKPVRALNINRMNNVTTL HLWQSAGRGLCTSATFKPIL FGENVLSGCLLEVGINENCT QLRENAVERLDSLIQATHVA MRGNSDYADLSDGWLEIIRV DAPDPGADPLASSVNGMCLD IPAHLSIRILISDAGAVEGI TQQEILGVETRFSSVNWQYQ CGLTCEHKADLLPISASVQF IKIPAQLPHPLTRFQINYTE YDCNRNEVCWPQLLYPWTQ |
| Function | Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction. |
| Protein Name | Tectonic-2 |
| Database Links | Reactome: R-HSA-5620912 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCytoplasmCytoskeletonCilium Basal BodyLocalizes At The Transition ZoneA Region Between The Basal Body And The Ciliary Axoneme |
| Alternative Antibody Names | Anti-Tectonic-2 antibodyAnti-TCTN2 antibodyAnti-C12orf38 antibodyAnti-TECT2 antibody |
Information sourced from Uniprot.org
