Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TCN1 (24-280) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TCN1 |
Gene ID: |
6947 |
Uniprot ID: |
TCO1_HUMAN |
Immunogen Region: |
24-280 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2). |
Immunogen Sequence: |
EICEVSEENYIRLKPLLNTM IQSNYNRGTSAVNVVLSLKL VGIQIQTLMQKMIQQIKYNV KSRLSDVSSGELALIILALG VCRNAEENLIYDYHLIDKLE NKFQAEIENMEAHNGTPLTN YYQLSLDVLALCLFNGNYST AEVVNHFTPENKNYYFGSQF SVDTGAMAVLALTCVKKSLI NGQIKADEGSLKNISIYTKS LVEKILSEKKENGLIGNTFS TGEAMQALFVSSDYYNEND |
Tissue Specificity | Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils. |
Post Translational Modifications | Contains about 30% carbohydrates. |
Function | Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach. |
Protein Name | Transcobalamin-1Tc-1HaptocorrinHcProtein RTranscobalamin ITc ITci |
Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-9758881Reactome: R-HSA-9758890 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Transcobalamin-1 antibodyAnti-Tc-1 antibodyAnti-Haptocorrin antibodyAnti-Hc antibodyAnti-Protein R antibodyAnti-Transcobalamin I antibodyAnti-Tc I antibodyAnti-Tci antibodyAnti-TCN1 antibodyAnti-TC1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance