| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TCN1 |
| Gene ID: | 6947 |
| Uniprot ID: | TCO1_HUMAN |
| Immunogen Region: | 24-280 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human TCN1 (NP_001053.2). |
| Immunogen Sequence: | EICEVSEENYIRLKPLLNTM IQSNYNRGTSAVNVVLSLKL VGIQIQTLMQKMIQQIKYNV KSRLSDVSSGELALIILALG VCRNAEENLIYDYHLIDKLE NKFQAEIENMEAHNGTPLTN YYQLSLDVLALCLFNGNYST AEVVNHFTPENKNYYFGSQF SVDTGAMAVLALTCVKKSLI NGQIKADEGSLKNISIYTKS LVEKILSEKKENGLIGNTFS TGEAMQALFVSSDYYNEND |
| Tissue Specificity | Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils. |
| Post Translational Modifications | Contains about 30% carbohydrates. |
| Function | Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach. |
| Protein Name | Transcobalamin-1Tc-1HaptocorrinHcProtein RTranscobalamin ITc ITci |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-9758881Reactome: R-HSA-9758890 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Transcobalamin-1 antibodyAnti-Tc-1 antibodyAnti-Haptocorrin antibodyAnti-Hc antibodyAnti-Protein R antibodyAnti-Transcobalamin I antibodyAnti-Tc I antibodyAnti-Tci antibodyAnti-TCN1 antibodyAnti-TC1 antibody |
Information sourced from Uniprot.org