Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Ribosome quality control complex subunit TCF25 is suitable for use in Western Blot and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000ELISA 1:5000-20000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | TCF25 |
Gene ID: | 22980 |
Uniprot ID: | TCF25_HUMAN |
Specificity: | TCF25 Polyclonal Antibody detects endogenous levels of protein. |
Immunogen: | Synthesized peptide derived from part of the human protein |
Function | Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. In the RQC complex, required to promote formation of 'Lys-48'-linked polyubiquitin chains during ubiquitination of incompletely synthesized proteins by LTN1. Also acts as a transcriptional repressor: represses transcription of SRF in vitro and so may play a role in heart development. May play a role in cell death control. |
Protein Name | Ribosome Quality Control Complex Subunit Tcf25Nuclear Localized Protein 1Transcription Factor 25Tcf-25 |
Cellular Localisation | NucleusCytoplasmCytosolMainly Nuclear |
Alternative Antibody Names | Anti-Ribosome Quality Control Complex Subunit Tcf25 antibodyAnti-Nuclear Localized Protein 1 antibodyAnti-Transcription Factor 25 antibodyAnti-Tcf-25 antibodyAnti-TCF25 antibodyAnti-KIAA1049 antibodyAnti-NULP1 antibodyAnti-FKSG26 antibody |
Information sourced from Uniprot.org