| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TBCC |
| Gene ID: | 6903 |
| Uniprot ID: | TBCC_HUMAN |
| Immunogen Region: | 1-346 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human TBCC (NP_003183.1). |
| Immunogen Sequence: | MESVSCSAAAVRTGDMESQR DLSLVPERLQRREQERQLEV ERRKQKRQNQEVEKENSHFF VATFARERAAVEELLERAES VERLEEAASRLQGLQKLIND SVFFLAAYDLRQGQEALARL QAALAERRRGLQPKKRFAFK TRGKDAASSTKVDAAPGIPP AVESIQDSPLPKKAEGDLGP SWVCGFSNLESQVLEKRASE LHQRDVLLTELSNCTVRLYG NPNTLRLTKAHSCKLLCGP |
| Tissue Specificity | Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level). |
| Function | Tubulin-folding protein.involved in the final step of the tubulin folding pathway. |
| Protein Name | Tubulin-Specific Chaperone CTubulin-Folding Cofactor CCfc |
| Database Links | Reactome: R-HSA-389977 |
| Cellular Localisation | CytoplasmDetected Predominantly In The Photoreceptor Connecting Cilium |
| Alternative Antibody Names | Anti-Tubulin-Specific Chaperone C antibodyAnti-Tubulin-Folding Cofactor C antibodyAnti-Cfc antibodyAnti-TBCC antibody |
Information sourced from Uniprot.org