Anti-TBCC antibody (1-346) (STJ119629)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal TBCC (1-346) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TBCC |
| Gene ID | 6903 |
| Uniprot ID | TBCC_HUMAN |
| Immunogen Region | 1-346 |
| Immunogen Sequence | MESVSCSAAAVRTGDMESQR DLSLVPERLQRREQERQLEV ERRKQKRQNQEVEKENSHFF VATFARERAAVEELLERAES VERLEEAASRLQGLQKLIND SVFFLAAYDLRQGQEALARL QAALAERRRGLQPKKRFAFK TRGKDAASSTKVDAAPGIPP AVESIQDSPLPKKAEGDLGP SWVCGFSNLESQVLEKRASE LHQRDVLLTELSNCTVRLYG NPNTLRLTKAHSCKLLCGP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human TBCC (NP_003183.1). |
Additional Info
| Tissue Specificity | Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecting cilium at the tips of the IS (at protein level). |
| Function | Tubulin-folding protein.involved in the final step of the tubulin folding pathway. |
| Protein Name | Tubulin-Specific Chaperone CTubulin-Folding Cofactor CCfc |
| Database Links | Reactome: R-HSA-389977 |
| Cellular Localisation | CytoplasmDetected Predominantly In The Photoreceptor Connecting Cilium |
| Alternative Antibody Names | Anti-Tubulin-Specific Chaperone C antibodyAnti-Tubulin-Folding Cofactor C antibodyAnti-Cfc antibodyAnti-TBCC antibody |
Information sourced from Uniprot.org