Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-TARBP1 (1322-1621) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TARBP1 |
Gene ID: |
6894 |
Uniprot ID: |
TARB1_HUMAN |
Immunogen Region: |
1322-1621 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3). |
Immunogen Sequence: |
QVESMHGAGNAKKNWQRIQE HFFFATFHPLKDYCLETIFY ILPRLSGLIEDEWITIDKFT RFTDVPLAAGFQWYLSQTQL SKLKPGDWSQQDIGTNLVEA DNQAEWTDVQKKIIPWNSRV SDLDLELLFQDRAARLGKSI SRLIVVASLIDKPTNLGGLC RTCEVFGASVLVVGSLQCIS DKQFQHLSVSAEQWLPLVEV KPPQLIDYLQQKKTEGYTII GVEQTAKSLDLTQYCFPEK |
Function | Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. (Microbial infection) In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. |
Protein Name | Probable Methyltransferase Tarbp1Tar Rna-Binding Protein 1Tar Rna-Binding Protein Of 185 KdaTrp-185 |
Alternative Antibody Names | Anti-Probable Methyltransferase Tarbp1 antibodyAnti-Tar Rna-Binding Protein 1 antibodyAnti-Tar Rna-Binding Protein Of 185 Kda antibodyAnti-Trp-185 antibodyAnti-TARBP1 antibodyAnti-TRM3 antibodyAnti-TRP185 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance