| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TARBP1 |
| Gene ID: | 6894 |
| Uniprot ID: | TARB1_HUMAN |
| Immunogen Region: | 1322-1621 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3). |
| Immunogen Sequence: | QVESMHGAGNAKKNWQRIQE HFFFATFHPLKDYCLETIFY ILPRLSGLIEDEWITIDKFT RFTDVPLAAGFQWYLSQTQL SKLKPGDWSQQDIGTNLVEA DNQAEWTDVQKKIIPWNSRV SDLDLELLFQDRAARLGKSI SRLIVVASLIDKPTNLGGLC RTCEVFGASVLVVGSLQCIS DKQFQHLSVSAEQWLPLVEV KPPQLIDYLQQKKTEGYTII GVEQTAKSLDLTQYCFPEK |
| Function | Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. (Microbial infection) In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. |
| Protein Name | Probable Methyltransferase Tarbp1Tar Rna-Binding Protein 1Tar Rna-Binding Protein Of 185 KdaTrp-185 |
| Alternative Antibody Names | Anti-Probable Methyltransferase Tarbp1 antibodyAnti-Tar Rna-Binding Protein 1 antibodyAnti-Tar Rna-Binding Protein Of 185 Kda antibodyAnti-Trp-185 antibodyAnti-TARBP1 antibodyAnti-TRM3 antibodyAnti-TRP185 antibody |
Information sourced from Uniprot.org