• Western blot analysis of extracts of various cell lines, using TARBP1 antibody (STJ11103358) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TARBP1 antibody (1322-1621) (STJ11103358)

SKU:
STJ11103358

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TARBP1 (1322-1621) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TARBP1
Gene ID: 6894
Uniprot ID: TARB1_HUMAN
Immunogen Region: 1322-1621
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1322-1621 of human TARBP1 (NP_005637.3).
Immunogen Sequence: QVESMHGAGNAKKNWQRIQE HFFFATFHPLKDYCLETIFY ILPRLSGLIEDEWITIDKFT RFTDVPLAAGFQWYLSQTQL SKLKPGDWSQQDIGTNLVEA DNQAEWTDVQKKIIPWNSRV SDLDLELLFQDRAARLGKSI SRLIVVASLIDKPTNLGGLC RTCEVFGASVLVVGSLQCIS DKQFQHLSVSAEQWLPLVEV KPPQLIDYLQQKKTEGYTII GVEQTAKSLDLTQYCFPEK
Function Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. (Microbial infection) In case of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Binding of TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone or in conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA.
Protein Name Probable Methyltransferase Tarbp1
Tar Rna-Binding Protein 1
Tar Rna-Binding Protein Of 185 Kda
Trp-185
Alternative Antibody Names Anti-Probable Methyltransferase Tarbp1 antibody
Anti-Tar Rna-Binding Protein 1 antibody
Anti-Tar Rna-Binding Protein Of 185 Kda antibody
Anti-Trp-185 antibody
Anti-TARBP1 antibody
Anti-TRM3 antibody
Anti-TRP185 antibody

Information sourced from Uniprot.org

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