| Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. |
| Protein Name | Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit CRna Polymerase I-Specific Tbp-Associated Factor 110 KdaTafi110Tata Box-Binding Protein-Associated Factor 1cTbp-Associated Factor 1cTranscription Initiation Factor Sl1/Tif-Ib Subunit C |
| Database Links | Reactome: R-HSA-427359Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit C antibodyAnti-Rna Polymerase I-Specific Tbp-Associated Factor 110 Kda antibodyAnti-Tafi110 antibodyAnti-Tata Box-Binding Protein-Associated Factor 1c antibodyAnti-Tbp-Associated Factor 1c antibodyAnti-Transcription Initiation Factor Sl1/Tif-Ib Subunit C antibodyAnti-TAF1C antibody |
Information sourced from Uniprot.org
