Anti-TAF1C antibody [R08-2B9] (STJA0034908)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human TAF1C
General Information
| Short Description | Rabbit monoclonal anti-TAF1C for use in WB and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-2B9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IP 1:20 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | TAF1C |
| Gene ID | 9013 |
| Uniprot ID | TAF1C_HUMAN |
| Immunogen | A synthetic peptide of human TAF1C |
Additional Info
| Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. |
| Protein Name | Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit CRna Polymerase I-Specific Tbp-Associated Factor 110 KdaTafi110Tata Box-Binding Protein-Associated Factor 1cTbp-Associated Factor 1cTranscription Initiation Factor Sl1/Tif-Ib Subunit C |
| Database Links | Reactome: R-HSA-427359Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit C antibodyAnti-Rna Polymerase I-Specific Tbp-Associated Factor 110 Kda antibodyAnti-Tafi110 antibodyAnti-Tata Box-Binding Protein-Associated Factor 1c antibodyAnti-Tbp-Associated Factor 1c antibodyAnti-Transcription Initiation Factor Sl1/Tif-Ib Subunit C antibodyAnti-TAF1C antibody |
Information sourced from Uniprot.org