| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAF1B |
| Gene ID: | 9014 |
| Uniprot ID: | TAF1B_HUMAN |
| Immunogen Region: | 369-588 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 369-588 of human TAF1B (NP_005671.2). |
| Immunogen Sequence: | LFLLDDSFEWSLSNLAEKHN EKNKKDKPWFDFRKWYQIMK KAFDEKKQKWEEARAKYLWK SEKPLYYSFVDKPVAYKKRE MVVNLQKQFSTLVESTATAG KKSPSSFQFNWTEEDTDRTC FHGHSLQGVLKEKGQSLLTK NSLYWLSTQKFCRCYCTHVT TYEESNYSLSYQFILNLFSF LLRIKTSLLHEEVSLVEKKL FEKKYSVKRKKSRSKKVRRH |
| Function | Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3. |
| Protein Name | Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit BRna Polymerase I-Specific Tbp-Associated Factor 63 KdaTafi63Tata Box-Binding Protein-Associated Factor 1bTbp-Associated Factor 1bTranscription Initiation Factor Sl1/Tif-Ib Subunit B |
| Database Links | Reactome: R-HSA-427359Reactome: R-HSA-427413Reactome: R-HSA-5250924Reactome: R-HSA-73762Reactome: R-HSA-73772Reactome: R-HSA-73863 |
| Cellular Localisation | NucleusNucleolus |
| Alternative Antibody Names | Anti-Tata Box-Binding Protein-Associated Factor Rna Polymerase I Subunit B antibodyAnti-Rna Polymerase I-Specific Tbp-Associated Factor 63 Kda antibodyAnti-Tafi63 antibodyAnti-Tata Box-Binding Protein-Associated Factor 1b antibodyAnti-Tbp-Associated Factor 1b antibodyAnti-Transcription Initiation Factor Sl1/Tif-Ib Subunit B antibodyAnti-TAF1B antibody |
Information sourced from Uniprot.org
