| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | TAF12 |
| Gene ID: | 6883 |
| Uniprot ID: | TAF12_HUMAN |
| Immunogen Region: | 1-161 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human TAF12 (NP_001128690.1). |
| Immunogen Sequence: | MNQFGPSALINLSNFSSIKP EPASTPPQGSMANSTAVVKI PGTPGAGGRLSPENNQVLTK KKLQDLVREVDPNEQLDEDV EEMLLQIADDFIESVVTAAC QLARHRKSSTLEVKDVQLHL ERQWNMWIPGFGSEEIRPYK KACTTEAHKQRMALIRKTTK K |
| Tissue Specificity | Ubiquitous. |
| Function | The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the TATA-binding protein-free TAF complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. |
| Protein Name | Transcription Initiation Factor Tfiid Subunit 12Transcription Initiation Factor Tfiid 20/15 Kda SubunitsTafii-20/Tafii-15Tafii20/Tafii15 |
| Database Links | Reactome: R-HSA-167161Reactome: R-HSA-167162Reactome: R-HSA-167172Reactome: R-HSA-3214847Reactome: R-HSA-674695Reactome: R-HSA-6804756Reactome: R-HSA-73776Reactome: R-HSA-73779Reactome: R-HSA-75953Reactome: R-HSA-76042 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Initiation Factor Tfiid Subunit 12 antibodyAnti-Transcription Initiation Factor Tfiid 20/15 Kda Subunits antibodyAnti-Tafii-20/Tafii-15 antibodyAnti-Tafii20/Tafii15 antibodyAnti-TAF12 antibodyAnti-TAF15 antibodyAnti-TAF2J antibodyAnti-TAFII20 antibody |
Information sourced from Uniprot.org
