Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-T (226-435) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:1000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
TBXT |
Gene ID: |
6862 |
Uniprot ID: |
TBXT_HUMAN |
Immunogen Region: |
226-435 |
Immunogen: |
RecombinanBrachyury fusion proBrachyuryein conBrachyuryaining a sequence corresponding Brachyuryo amino acids 226-435 of human Brachyury (NP_003172.1). |
Immunogen Sequence: |
HKEMMEEPGDSQQPGYSQWG WLLPGTSTLCPPANPHPQFG GALSLPSTHSCDRYPTLRSH RSSPYPSPYAHRNNSPTYSD NSPACLSMLQSHDNWSSLGM PAHPSMLPVSHNASPPTSSS QYPSLWSVSNGAVTPGSQAA AVSNGLGAQFFRGSPAHYTP LTHPVSAPSSSGSPLYEGAA AATDIVDSQYDAAAQGRLIA SWTPVSPPSM |
Tissue Specificity | Detected in testis, but not in other, normal tissues. Detected in lung tumors (at protein level). |
Function | Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. |
Protein Name | T-Box Transcription Factor TBrachyury ProteinProtein T |
Database Links | Reactome: R-HSA-9733709Reactome: R-HSA-9754189Reactome: R-HSA-9758919Reactome: R-HSA-9793380Reactome: R-HSA-9796292Reactome: R-HSA-9823730 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-T-Box Transcription Factor T antibodyAnti-Brachyury Protein antibodyAnti-Protein T antibodyAnti-TBXT antibodyAnti-T antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance